Human ANKRD16 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ANKRD16
Locus ID	54522
Kit Components	GA110156G1, ANKRD16 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA110156G2, ANKRD16 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA110156G3, ANKRD16 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001009941, NM_001009942, NM_001009943, NM_019046
Synonyms	ankyrin repeat domain 16; OTTHUMP00000019019; OTTHUMP00000044872
Summary	Required to prevent the misactivation of serine (Ser) with tRNA(Ala) by promoting the hydrolysis of Ser-mischarged tRNA(Ala), thereby playing a role in translational fidelity. Binds directly to the catalytic domain of AARS/AlaRS and captures Ser that is misactivated by AARS/AlaRS, preventing the charging of Ser adenylates to tRNA(Ala) and precluding Ser misincorporation in nascent peptides.[UniProtKB/Swiss-Prot Function]

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.