Human DGCR8 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	DGCR8
Locus ID	54487
Kit Components	GA110131G1, DGCR8 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA110131G2, DGCR8 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA110131G3, DGCR8 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001190326, NM_022720
Synonyms	C22orf12; DGCRK6; Gy1; pasha
Summary	This gene encodes a subunit of the microprocessor complex which mediates the biogenesis of microRNAs from the primary microRNA transcript. The encoded protein is a double-stranded RNA binding protein that functions as the non-catalytic subunit of the microprocessor complex. This protein is required for binding the double-stranded RNA substrate and facilitates cleavage of the RNA by the ribonuclease III protein, Drosha. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010]

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