Human ETAA1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ETAA1
Locus ID	54465
Kit Components	GA110116G1, ETAA1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA110116G2, ETAA1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA110116G3, ETAA1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_019002
Synonyms	ETAA16
Summary	Replication stress response protein that accumulates at DNA damage sites and promotes replication fork progression and integrity (PubMed:27601467, PubMed:27723720, PubMed:27723717). Recruited to stalled replication forks via interaction with the RPA complex and directly stimulates ATR kinase activity independently of TOPBP1 (PubMed:27723720, PubMed:27723717). Probably only regulates a subset of ATR targets (PubMed:27723720, PubMed:27723717).[UniProtKB/Swiss-Prot Function]

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