Human STYXL1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	STYXL1
Locus ID	51657
Kit Components	GA109927G1, STYXL1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA109927G2, STYXL1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA109927G3, STYXL1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001317785, NM_001317786, NM_001317787, NM_001317788, NM_001317789, NM_016086, NR_134486, NR_134487
Synonyms	DUSP24; MK-STYX; MKSTYX
Summary	Catalytically inactive phosphatase (PubMed:20180778, PubMed:23163895). By binding to G3BP1, inhibits the formation of G3BP1-induced stress granules (PubMed:20180778, PubMed:23163895). Does not act by protecting the dephosphorylation of G3BP1 at 'Ser-149' (PubMed:23163895). Inhibits PTPMT1 phosphatase activity (PubMed:24709986). By inhibiting PTPMT1, positively regulates intrinsic apoptosis (PubMed:21262771). May play a role in the formation of neurites during neuronal development (PubMed:29250526).[UniProtKB/Swiss-Prot Function]

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