Human NIPA (ZC3HC1) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ZC3HC1
Locus ID	51530
Kit Components	GA109856G1, NIPA gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA109856G2, NIPA gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA109856G3, NIPA gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001282190, NM_001282191, NM_016478, NM_001363701
Synonyms	HSPC216; NIPA
Summary	This gene encodes an F-box-containing protein that is a component of an SCF-type E3 ubiquitin ligase complex that regulates the onset of cell division. The G2/M transition in the cell cycle requires the interaction of the proteins cyclin B1 and cyclin-dependent kinase 1. The activated ubiquitin ligase complex targets the protein cyclin B1 for degradation, preventing this transition to mitosis. [provided by RefSeq, Aug 2013]

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