Human Leucyl tRNA synthetase (LARS) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	LARS1
Locus ID	51520
Kit Components	GA109848G1, Leucyl tRNA synthetase gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA109848G2, Leucyl tRNA synthetase gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA109848G3, Leucyl tRNA synthetase gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001317964, NM_001317965, NM_016460, NM_020117
Synonyms	hr025Cl; HSPC192; ILFS1; LARS1; LEURS; LEUS; LFIS; LRS; PIG44; RNTLS
Summary	This gene encodes a cytosolic leucine-tRNA synthetase, a member of the class I aminoacyl-tRNA synthetase family. The encoded enzyme catalyzes the ATP-dependent ligation of L-leucine to tRNA(Leu). It is found in the cytoplasm as part of a multisynthetase complex and interacts with the arginine tRNA synthetase through its C-terminal domain. A mutation in this gene was found in affected individuals with infantile liver failure syndrome 1. Alternatively spliced transcript variants of this gene have been observed. [provided by RefSeq, Dec 2015]

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.