Human NCKIPSD activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	NCKIPSD
Locus ID	51517
Kit Components	GA109847G1, NCKIPSD gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA109847G2, NCKIPSD gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA109847G3, NCKIPSD gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_016453, NM_184231
Synonyms	AF3P21; DIP; DIP1; ORF1; SPIN90; VIP54; WASLBP; WISH
Summary	The protein encoded by this gene contains a nuclear localization signal. It plays a role in signal transduction, and may function in the maintenance of sarcomeres and in the assembly of myofibrils into sarcomeres. It also plays an important role in stress fiber formation This protein is involved in the formation and maintenance of dendritic spines, and modulates synaptic activity in neurons. The gene is involved in therapy-related leukemia by a chromosomal translocation t(3;11)(p21;q23) that involves this gene and the myeloid/lymphoid leukemia gene. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Aug 2019]

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