Human RTF2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	RTF2
Locus ID	51507
Kit Components	GA109842G1, RTF2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA109842G2, RTF2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA109842G3, RTF2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001283035, NM_001283036, NM_001283037, NM_016407
Synonyms	C20orf43; CDAO5; HSPC164; SHUJUN-3
Summary	Replication termination factor which is a component of the elongating replisome (Probable). Required for ATR pathway signaling upon DNA damage and has a positive activity during DNA replication. Might function to facilitate fork pausing at replication fork barriers like the rDNA. May be globally required to stimulate ATR signaling after the fork stalls or encounters a lesion (Probable). Interacts with nascent DNA (PubMed:29290612).[UniProtKB/Swiss-Prot Function]

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