Human C9orf114 (SPOUT1) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	SPOUT1
Locus ID	51490
Kit Components	GA109831G1, C9orf114 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA109831G2, C9orf114 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA109831G3, C9orf114 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_016390
Synonyms	C9orf114; CENP-32; HSPC109
Summary	Required for association of the centrosomes with the poles of the bipolar mitotic spindle during metaphase (PubMed:20813266, PubMed:25657325). Also involved in chromosome alignment (PubMed:20813266). May promote centrosome maturation probably by recruiting A-kinase anchor protein AKAP9 to centrosomes in early mitosis (PubMed:25657325). Binds specifically to miRNA MIR145 hairpin, regulates MIR145 expression at a postranscriptional level (PubMed:28431233).[UniProtKB/Swiss-Prot Function]

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