Human HSPC014 (POMP) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	POMP
Locus ID	51371
Kit Components	GA109770G1, HSPC014 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA109770G2, HSPC014 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA109770G3, HSPC014 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_015932
Synonyms	C13orf12; HSPC014; PNAS-110; UMP1
Summary	The protein encoded by this gene is a molecular chaperone that binds 20S preproteasome components and is essential for 20S proteasome formation. The 20S proteasome is the proteolytically active component of the 26S proteasome complex. The encoded protein is degraded before the maturation of the 20S proteasome is complete. A variant in the 5' UTR of this gene has been associated with KLICK syndrome, a rare skin disorder.[provided by RefSeq, Aug 2010]

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