Human GODZ (ZDHHC3) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ZDHHC3
Locus ID	51304
Kit Components	GA109723G1, GODZ gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA109723G2, GODZ gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA109723G3, GODZ gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001135179, NM_001135180, NM_016598, NM_001330761, NM_001349376, NM_001349377, NM_001349378, NM_001349379, NM_001349380, NM_001349381, NR_146161, NR_146162, NR_146163
Synonyms	DHHC-3; GODZ; ZNF373
Summary	Palmitoyltransferase with broad specificity (PubMed:21926431, PubMed:23034182). Palmitoylates GABA receptors on their gamma subunit (GABRG1, GABRG2 and GABRG3), which regulates synaptic clustering and/or cell surface stability (By similarity). Palmitoylates glutamate receptors GRIA1 and GRIA2, which leads to their retention in Golgi. May also palmitoylate DLG4, DNAJC5 and SNAP25 (By similarity).[UniProtKB/Swiss-Prot Function]

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