Human PHF20 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	PHF20
Locus ID	51230
Kit Components	GA109662G1, PHF20 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA109662G2, PHF20 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA109662G3, PHF20 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_016436
Synonyms	C20orf104; GLEA2; HCA58; NZF; TDRD20A; TZP
Summary	Methyllysine-binding protein, component of the MOF histone acetyltransferase protein complex. Not required for maintaining the global histone H4 'Lys-16' acetylation (H4K16ac) levels or locus specific histone acetylation, but instead works downstream in transcriptional regulation of MOF target genes (By similarity). As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. Contributes to methyllysine-dependent p53/TP53 stabilization and up-regulation after DNA damage.[UniProtKB/Swiss-Prot Function]

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