Human Glycoprotein VI (GP6) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	GP6
Locus ID	51206
Kit Components	GA109650G1, Glycoprotein VI gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA109650G2, Glycoprotein VI gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA109650G3, Glycoprotein VI gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001083899, NM_001256017, NM_016363
Synonyms	BDPLT11; GPIV; GPVI
Summary	This gene encodes a platelet membrane glycoprotein of the immunoglobulin superfamily. The encoded protein is a receptor for collagen and plays a critical role in collagen-induced platelet aggregation and thrombus formation. The encoded protein forms a complex with the Fc receptor gamma-chain that initiates the platelet activation signaling cascade upon collagen binding. Mutations in this gene are a cause of platelet-type bleeding disorder-11 (BDPLT11). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]

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