Human CHREBP (MLXIPL) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	MLXIPL
Locus ID	51085
Kit Components	GA109550G1, CHREBP gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA109550G2, CHREBP gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA109550G3, CHREBP gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_015977, NM_032951, NM_032952, NM_032953, NM_032954, NM_032994, NR_134541
Synonyms	bHLHd14; CHREBP; MIO; MLX; MONDOB; WBSCR14; WS-bHLH
Summary	This gene encodes a basic helix-loop-helix leucine zipper transcription factor of the Myc/Max/Mad superfamily. This protein forms a heterodimeric complex and binds and activates, in a glucose-dependent manner, carbohydrate response element (ChoRE) motifs in the promoters of triglyceride synthesis genes. The gene is deleted in Williams-Beuren syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at chromosome 7q11.23. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.