Human DERL2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	DERL2
Locus ID	51009
Kit Components	GA109493G1, DERL2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA109493G2, DERL2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA109493G3, DERL2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001304777, NM_001304779, NM_016041, NR_130905, NR_130906
Synonyms	CGI-101; derlin-2; DERtrin-2; F-LAN-1; F-LANa; FLANa
Summary	Proteins that are unfolded or misfolded in the endoplasmic reticulum (ER) must be refolded or degraded to maintain the homeostasis of the ER. DERL2 is involved in the degradation of misfolded glycoproteins in the ER (Oda et al., 2006 [PubMed 16449189]).[supplied by OMIM, Mar 2008]

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