Human PAR6 (PARD6A) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	PARD6A
Locus ID	50855
Kit Components	GA109470G1, PAR6 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA109470G2, PAR6 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA109470G3, PAR6 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001037281, NM_016948
Synonyms	PAR-6A; PAR6; PAR6alpha; PAR6C; TAX40; TIP-40
Summary	This gene is a member of the PAR6 family and encodes a protein with a PSD95/Discs-large/ZO1 (PDZ) domain and a semi-Cdc42/Rac interactive binding (CRIB) domain. This cell membrane protein is involved in asymmetrical cell division and cell polarization processes as a member of a multi-protein complex. The protein also has a role in the epithelial-to-mesenchymal transition (EMT) that characterizes the invasive phenotype associated with metastatic carcinomas. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]

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