Human HP1BP3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	HP1BP3
Locus ID	50809
Kit Components	GA109452G1, HP1BP3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA109452G2, HP1BP3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA109452G3, HP1BP3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_016287
Synonyms	HP1-BP74; HP1BP74
Summary	Component of heterochromatin that maintains heterochromatin integrity during G1/S progression and regulates the duration of G1 phase to critically influence cell proliferative capacity (PubMed:24830416). Mediates chromatin condensation during hypoxia, leading to increased tumor cell viability, radio-resistance, chemo-resistance and self-renewal(PubMed:25100860).[UniProtKB/Swiss-Prot Function]

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