Human KCNIP1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	KCNIP1
Locus ID	30820
Kit Components	GA109390G1, KCNIP1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA109390G2, KCNIP1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA109390G3, KCNIP1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001034837, NM_001034838, NM_001278339, NM_001278340, NM_014592
Synonyms	KCHIP1; VABP
Summary	This gene encodes a member of the family of cytosolic voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belong to the neuronal calcium sensor (NCS) family of the calcium binding EF-hand proteins. They associate with Kv4 alpha subunits to form native Kv4 channel complexes. The encoded protein may regulate rapidly inactivating (A-type) currents, and hence neuronal membrane excitability, in response to changes in the concentration of intracellular calcium. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2013]

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