Human EML4 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	EML4
Locus ID	27436
Kit Components	GA109149G1, EML4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA109149G2, EML4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA109149G3, EML4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001145076, NM_019063
Synonyms	C2orf2; ELP120; EMAP-4; EMAPL4; ROPP120
Summary	This gene is a member of the echinoderm microtubule associated protein-like family. The encoded WD-repeat protein may be involved in microtubule formation. Abnormal fusion of parts of this gene with portions of the anaplastic lymphoma receptor tyrosine kinase gene, which generates EML4-ALK fusion transcripts, is one of the primary mutations associated with non-small cell lung cancer. Alternative splicing of this gene results in two transcript variants. [provided by RefSeq, Jan 2015]

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