Human ZNF364 (RNF115) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	RNF115
Locus ID	27246
Kit Components	GA109082G1, ZNF364 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA109082G2, ZNF364 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA109082G3, ZNF364 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_014455
Synonyms	BCA2; ZNF364
Summary	E3 ubiquitin-protein ligase that mediates E2-dependent, 'Lys-48'- and/or 'Lys-63'-linked polyubiquitination of substrates and may play a role in diverse biological processes. Through their polyubiquitination, may play a role in the endosomal trafficking and degradation of membrane receptors including EGFR, FLT3, MET and CXCR4.[UniProtKB/Swiss-Prot Function]

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