Human IL17B activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	IL17B
Locus ID	27190
Kit Components	GA109060G1, IL17B gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA109060G2, IL17B gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA109060G3, IL17B gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001317987, NM_014443
Synonyms	IL-17B; IL-20; NIRF; ZCYTO7
Summary	The protein encoded by this gene is a T cell-derived cytokine that shares sequence similarity with IL17. This cytokine was reported to stimulate the release of TNF alpha (TNF) and IL1 beta (IL1B) from a monocytic cell line. Immunohistochemical analysis of several nerve tissues indicated that this cytokine is primarily localized to neuronal cell bodies. Alternative splicing results in multiple splice variants. [provided by RefSeq, Dec 2015]

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