Human TPK1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	TPK1
Locus ID	27010
Kit Components	GA108964G1, TPK1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA108964G2, TPK1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA108964G3, TPK1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001042482, NM_022445, NM_001350879, NM_001350880, NM_001350881, NM_001350882, NM_001350883, NM_001350884, NM_001350885, NM_001350886, NM_001350887, NM_001350889, NM_001350893, NM_001350894, NM_001350895, NR_146935, NR_146936, NR_146934
Synonyms	HTPK1; PP20; THMD5
Summary	The protein encoded by this gene functions as a homodimer and catalyzes the conversion of thiamine to thiamine pyrophosphate, a cofactor for some enzymes of the glycolytic and energy production pathways. Defects in this gene are a cause of thiamine metabolism dysfunction syndrome-5. [provided by RefSeq, Apr 2017]

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