Human PABP (PABPC1) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	PABPC1
Locus ID	26986
Kit Components	GA108954G1, PABP gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA108954G2, PABP gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA108954G3, PABP gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_002568
Synonyms	PAB1; PABP; PABP1; PABPC2; PABPL1
Summary	This gene encodes a poly(A) binding protein. The protein shuttles between the nucleus and cytoplasm and binds to the 3' poly(A) tail of eukaryotic messenger RNAs via RNA-recognition motifs. The binding of this protein to poly(A) promotes ribosome recruitment and translation initiation; it is also required for poly(A) shortening which is the first step in mRNA decay. The gene is part of a small gene family including three protein-coding genes and several pseudogenes.[provided by RefSeq, Aug 2010]

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