Human HBP1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	HBP1
Locus ID	26959
Kit Components	GA108948G1, HBP1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA108948G2, HBP1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA108948G3, HBP1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001244262, NM_012257
Summary	Transcriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5'-TTCATTCATTCA-3'. Binding to the H1F0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4.[UniProtKB/Swiss-Prot Function]

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