Human PLEK2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	PLEK2
Locus ID	26499
Kit Components	GA108874G1, PLEK2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA108874G2, PLEK2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA108874G3, PLEK2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_016445
Synonyms	pleckstrin 2; pleckstrin 2 homolog
Summary	The protein encoded by this gene associates with membrane-bound phosphatidylinositols generated by phosphatidylinositol 3-kinase. The encoded protein then interacts with the actin cytoskeleton to induce cell spreading. In conjunction with complement component 1, q subcomponent, B chain (C1QB), this gene shows an increase in expression in melanoma cells and may serve as an accurate biomarker for the disease. [provided by RefSeq, Dec 2015]

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