Human IRF2BP1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	IRF2BP1
Locus ID	26145
Kit Components	GA108771G1, IRF2BP1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA108771G2, IRF2BP1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA108771G3, IRF2BP1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_015649
Synonyms	DKFZp434M154
Summary	Acts as a transcriptional corepressor in a IRF2-dependent manner; this repression is not mediated by histone deacetylase activities. May act as an E3 ligase towards JDP2, enhancing its polyubiquitination. Represses ATF2-dependent transcriptional activation.[UniProtKB/Swiss-Prot Function]

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