Human HERC4 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	HERC4
Locus ID	26091
Kit Components	GA108745G1, HERC4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA108745G2, HERC4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA108745G3, HERC4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001017972, NM_001278185, NM_001278186, NM_001278187, NM_015601, NM_022079
Synonyms	DKFZP564G092; KIAA1593
Summary	HERC4 belongs to the HERC family of ubiquitin ligases, all of which contain a HECT domain and at least 1 RCC1 (MIM 179710)-like domain (RLD). The 350-amino acid HECT domain is predicted to catalyze the formation of a thioester with ubiquitin before transferring it to a substrate, and the RLD is predicted to act as a guanine nucleotide exchange factor for small G proteins (Hochrainer et al., 2005 [PubMed 15676274]).[supplied by OMIM, Mar 2008]

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