Human GIGYF2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	GIGYF2
Locus ID	26058
Kit Components	GA108729G1, GIGYF2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA108729G2, GIGYF2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA108729G3, GIGYF2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001103146, NM_001103147, NM_001103148, NM_015575, NR_103492, NR_103493, NR_103494, NR_103495
Synonyms	GYF2; PARK11; PERQ2; PERQ3; TNRC15
Summary	This gene contains CAG trinucleotide repeats and encodes a protein containing several stretches of polyglutamine residues. The encoded protein may be involved in the regulation of tyrosine kinase receptor signaling. This gene is located in a chromosomal region that was genetically linked to Parkinson disease type 11, and mutations in this gene were thought to be causative for this disease. However, more recent studies in different populations have been unable to replicate this association. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013]

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