Human DNAH1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	DNAH1
Locus ID	25981
Kit Components	GA108674G1, DNAH1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA108674G2, DNAH1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA108674G3, DNAH1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_015512
Synonyms	DNAHC1; HDHC7; HL-11; HL11; HSRF-1; XLHSRF-1
Summary	This gene encodes an inner dynein arm heavy chain that provides structural support between the radial spokes and the outer doublet of the sperm tail. Naturally occurring mutations in this gene are associated with primary ciliary dyskinesia and multiple morphological anomalies of the flagella that result in asthenozoospermia and male infertility. Mice with a homozygous knockout of the orthologous gene are viable but have reduced sperm motility and are infertile. [provided by RefSeq, Feb 2017]

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