Human HDPTP (PTPN23) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	PTPN23
Locus ID	25930
Kit Components	GA108639G1, HDPTP gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA108639G2, HDPTP gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA108639G3, HDPTP gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001304482, NM_015466
Synonyms	HD-PTP; HDPTP; PTP-TD14
Summary	This gene encodes a member of the non-receptor type protein-tyrosine phosphatase family. The encoded protein may be involved in the regulation of small nuclear ribonucleo protein assembly and pre-mRNA splicing by modifying the survival motor neuron (SMN) complex. The encoded protein additionally plays a role in ciliogenesis and is part of endosomal sorting complex required for transport (ESCRT) pathways. This gene may serve a tumor suppressor function. [provided by RefSeq, Jul 2016]

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