Human SOSTDC1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	SOSTDC1
Locus ID	25928
Kit Components	GA108637G1, SOSTDC1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA108637G2, SOSTDC1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA108637G3, SOSTDC1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_015464
Synonyms	CDA019; ECTODIN; USAG1
Summary	This gene is a member of the sclerostin family and encodes an N-glycosylated, secreted protein with a C-terminal cystine knot-like domain. This protein functions as a bone morphogenetic protein (BMP) antagonist. Specifically, it directly associates with BMPs, prohibiting them from binding their receptors, thereby regulating BMP signaling during cellular proliferation, differentiation, and programmed cell death. [provided by RefSeq, Jul 2008]

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