Human C11orf51 (ANAPC15) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ANAPC15
Locus ID	25906
Kit Components	GA108621G1, C11orf51 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA108621G2, C11orf51 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA108621G3, C11orf51 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001278485, NM_001278486, NM_001278487, NM_001278488, NM_001278489, NM_001278490, NM_001278491, NM_001278492, NM_001278493, NM_001278494, NM_001330321, NM_014042
Synonyms	APC15; C11orf51; HSPC020
Summary	Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. In the complex, plays a role in the release of the mitotic checkpoint complex (MCC) from the APC/C: not required for APC/C activity itself, but promotes the turnover of CDC20 and MCC on the APC/C, thereby participating in the responsiveness of the spindle assembly checkpoint. Also required for degradation of CDC20.[UniProtKB/Swiss-Prot Function]

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