Human Pirh2 (RCHY1) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	RCHY1
Locus ID	25898
Kit Components	GA108615G1, Pirh2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA108615G2, Pirh2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA108615G3, Pirh2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001008925, NM_001009922, NM_001278536, NM_001278537, NM_001278538, NM_001278539, NM_015436, NR_037913, NR_037914, NR_103723, NR_103724, NR_103725
Synonyms	ARNIP; CHIMP; hARNIP; PIRH2; PIRH2E; PIRH2F; PRO1996; RNF199; ZNF363
Summary	The protein encoded by this gene has ubiquitin ligase activity. It mediates E3-dependent ubiquitination and proteasomal degradation of target proteins, including tumor protein 53, histone deacetylase 1, and cyclin-dependent kinase inhibitor 1B, thus regulating their levels and cell cycle progression. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jun 2013]

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