Human DORFIN (RNF19A) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	RNF19A
Locus ID	25897
Kit Components	GA108614G1, DORFIN gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA108614G2, DORFIN gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA108614G3, DORFIN gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001280539, NM_015435, NM_183419, NM_001353837, NM_001353838
Synonyms	RNF19
Summary	This gene encodes a member of the ring between ring fingers (RBR) protein family, and the encoded protein contains two RING-finger motifs and an in between RING fingers motif. This protein is an E3 ubiquitin ligase that is localized to Lewy bodies, and ubiquitylates synphilin-1, which is an interacting protein of alpha synuclein in neurons. The encoded protein may be involved in amyotrophic lateral sclerosis and Parkinson's disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]

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