Human Protein Kinase D2 (PRKD2) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	PRKD2
Locus ID	25865
Kit Components	GA108594G1, Protein Kinase D2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA108594G2, Protein Kinase D2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA108594G3, Protein Kinase D2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001079880, NM_001079881, NM_001079882, NM_016457
Synonyms	HSPC187; nPKC-D2; PKD2
Summary	The protein encoded by this gene belongs to the protein kinase D (PKD) family of serine/threonine protein kinases. This kinase can be activated by phorbol esters as well as by gastrin via the cholecystokinin B receptor (CCKBR) in gastric cancer cells. It can bind to diacylglycerol (DAG) in the trans-Golgi network (TGN) and may regulate basolateral membrane protein exit from TGN. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

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