Human FBXL2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	FBXL2
Locus ID	25827
Kit Components	GA108566G1, FBXL2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA108566G2, FBXL2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA108566G3, FBXL2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001171713, NM_012157, NM_001349316, NM_001349319, NM_001349320, NM_001349321, NM_001349322, NM_001349323, NM_001349324, NM_001349325, NM_001349326, NR_146121, NR_146122, NR_146123, NR_146124, NR_146125, NR_146126, NR_146127, NR_146128, NR_146129, NR_146130, NR_146131, NR_146132, NR_146133, NR_146134, NR_146135
Synonyms	FBL2; FBL3
Summary	This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains 12 tandem leucine-rich repeats. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2010]

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