Human ATXN10 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ATXN10
Locus ID	25814
Kit Components	GA108555G1, ATXN10 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA108555G2, ATXN10 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA108555G3, ATXN10 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001167621, NM_013236
Synonyms	E46L; HUMEEP; SCA10
Summary	This gene encodes a protein that may function in neuron survival, neuron differentiation, and neuritogenesis. These roles may be carried out via activation of the mitogen-activated protein kinase cascade. Expansion of an ATTCT repeat from 9-32 copies to 800-4500 copies in an intronic region of this locus has been associated with spinocerebellar ataxia, type 10. Alternatively spliced transcript variants have been described.[provided by RefSeq, Jul 2016]

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