Human RAB3GAP2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	RAB3GAP2
Locus ID	25782
Kit Components	GA108533G1, RAB3GAP2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA108533G2, RAB3GAP2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA108533G3, RAB3GAP2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_012414, N93244
Synonyms	p150; RAB3-GAP150; RAB3GAP150; SPG69; WARBM2
Summary	The protein encoded by this gene belongs to the RAB3 protein family, members of which are involved in regulated exocytosis of neurotransmitters and hormones. This protein forms the Rab3 GTPase-activating complex with RAB3GAP1, where it constitutes the regulatory subunit, whereas the latter functions as the catalytic subunit. This gene has the highest level of expression in the brain, consistent with it having a key role in neurodevelopment. Mutations in this gene are associated with Martsolf syndrome.[provided by RefSeq, Oct 2009]

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