Human LYPLA3 (PLA2G15) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	PLA2G15
Locus ID	23659
Kit Components	GA108466G1, LYPLA3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA108466G2, LYPLA3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA108466G3, LYPLA3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_012320, NM_001363551
Synonyms	ACS; GXVPLA2; LLPL; LPLA2; LYPLA3
Summary	Lysophospholipases are enzymes that act on biological membranes to regulate the multifunctional lysophospholipids. The protein encoded by this gene hydrolyzes lysophosphatidylcholine to glycerophosphorylcholine and a free fatty acid. This enzyme is present in the plasma and thought to be associated with high-density lipoprotein. A later paper contradicts the function of this gene. It demonstrates that this gene encodes a lysosomal enzyme instead of a lysophospholipase and has both calcium-independent phospholipase A2 and transacylase activities. [provided by RefSeq, Jul 2008]

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