Human PLD3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	PLD3
Locus ID	23646
Kit Components	GA108458G1, PLD3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA108458G2, PLD3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA108458G3, PLD3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001031696, NM_001291311, NM_012268
Synonyms	AD19; HU-K4; HUK4
Summary	This gene encodes a member of the phospholipase D (PLD) family of enzymes that catalyze the hydrolysis of membrane phospholipids. The encoded protein is a single-pass type II membrane protein and contains two PLD phosphodiesterase domains. This protein influences processing of amyloid-beta precursor protein. Mutations in this gene are associated with Alzheimer disease risk. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Apr 2014]

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