Human HSPBP1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	HSPBP1
Locus ID	23640
Kit Components	GA108453G1, HSPBP1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA108453G2, HSPBP1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA108453G3, HSPBP1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001130106, NM_001297600, NM_012267
Synonyms	FES1
Summary	Inhibits HSPA1A chaperone activity by changing the conformation of the ATP-binding domain of HSPA1A and interfering with ATP binding. Interferes with ubiquitination mediated by STUB1 and inhibits chaperone-assisted degradation of immature CFTR.[UniProtKB/Swiss-Prot Function]

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