Human ZIM2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ZIM2
Locus ID	23619
Kit Components	GA108438G1, ZIM2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA108438G2, ZIM2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA108438G3, ZIM2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001146326, NM_001146327, NM_015363, NM_001369772, NM_001369773, NR_163141, NR_163142, NM_001369770, NM_001369771, NM_001369774, NR_163140, NR_163143
Synonyms	ZNF656
Summary	In human, ZIM2 and PEG3 (GeneID:5178) are two distinct genes that share a set of 5' exons and have a common promoter, and both genes are paternally expressed. Alternative splicing events connect the shared exons either with the remaining 4 exons unique to ZIM2, or with the remaining 2 exons unique to PEG3. This is in contrast to mouse and cow, where ZIM2 and PEG3 genes do not share exons in common, and the imprinting status of ZIM2 is also not conserved amongst mammals. Additional 5' alternatively spliced transcripts encoding the same protein have been found for the human ZIM2 gene. [provided by RefSeq, Oct 2010]

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