Human MAN1 (LEMD3) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	LEMD3
Locus ID	23592
Kit Components	GA108420G1, MAN1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA108420G2, MAN1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA108420G3, MAN1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001167614, NM_014319
Synonyms	MAN1
Summary	This locus encodes a LEM domain-containing protein. The encoded protein functions to antagonize transforming growth factor-beta signaling at the inner nuclear membrane. Two transcript variants encoding different isoforms have been found for this gene. Mutations in this gene have been associated with osteopoikilosis, Buschke-Ollendorff syndrome and melorheostosis.[provided by RefSeq, Nov 2009]

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