Human ICE1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ICE1
Locus ID	23379
Kit Components	GA108262G1, ICE1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA108262G2, ICE1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA108262G3, ICE1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_015325
Synonyms	KIAA0947
Summary	Component of the little elongation complex (LEC), a complex required to regulate small nuclear RNA (snRNA) gene transcription by RNA polymerase II and III (PubMed:22195968, PubMed:23932780). Specifically acts as a scaffold protein that promotes the LEC complex formation and recruitment and RNA polymerase II occupancy at snRNA genes in subnuclear bodies (PubMed:23932780).[UniProtKB/Swiss-Prot Function]

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