Human ASPP1 (PPP1R13B) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	PPP1R13B
Locus ID	23368
Kit Components	GA108255G1, ASPP1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA108255G2, ASPP1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA108255G3, ASPP1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_015316
Synonyms	ASPP1; p53BP2-like; p85
Summary	This gene encodes a member of the ASPP (apoptosis-stimulating protein of p53) family of p53 interacting proteins. The protein contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. ASPP proteins are required for the induction of apoptosis by p53-family proteins. They promote DNA binding and transactivation of p53-family proteins on the promoters of proapoptotic genes. Expression of this gene is regulated by the E2F transcription factor. [provided by RefSeq, Jul 2008]

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