Human DNAJC13 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	DNAJC13
Locus ID	23317
Kit Components	GA108215G1, DNAJC13 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA108215G2, DNAJC13 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA108215G3, DNAJC13 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001329126, NM_015268, NM_173823
Synonyms	PARK21; RME8
Summary	This gene encodes a member of the Dnaj protein family whose members act as co-chaperones of a partner heat-shock protein by binding to the latter and stimulating ATP hydrolysis. The encoded protein associates with the heat-shock protein Hsc70 and plays a role in clathrin-mediated endocytosis. It may also be involved in post-endocytic transport mechanisms via its associations with other proteins, including the sorting nexin SNX1. Mutations in this gene are associated with Parkinson's disease. [provided by RefSeq, Jun 2016]

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