Human LPHN3 (ADGRL3) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ADGRL3
Locus ID	23284
Kit Components	GA108189G1, LPHN3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA108189G2, LPHN3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA108189G3, LPHN3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001322246, NM_001322402, NM_015236
Synonyms	CIRL3; CL3; LEC3; LPHN3
Summary	This gene encodes a member of the latrophilin subfamily of G-protein coupled receptors (GPCR). Latrophilins may function in both cell adhesion and signal transduction. In experiments with non-human species, endogenous proteolytic cleavage within a cysteine-rich GPS (G-protein-coupled-receptor proteolysis site) domain resulted in two subunits (a large extracellular N-terminal cell adhesion subunit and a subunit with substantial similarity to the secretin/calcitonin family of GPCRs) being non-covalently bound at the cell membrane. [provided by RefSeq, Jul 2008]

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