Human DTX4 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	DTX4
Locus ID	23220
Kit Components	GA108137G1, DTX4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA108137G2, DTX4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA108137G3, DTX4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001300727, NM_015177
Synonyms	RNF155
Summary	Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations (By similarity). Functions as a ubiquitin ligase protein in vivo, mediating 'Lys48'-linked polyubiquitination and promoting degradation of TBK1, targeting to TBK1 requires interaction with NLRP4.[UniProtKB/Swiss-Prot Function]

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