Human CYFIP1 activation kit by CRISPRa

CAT#: GA108110

CYFIP1 CRISPRa kit - CRISPR gene activation of human cytoplasmic FMR1 interacting protein 1



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CNY 12255.00


货期*
4周

规格
    • 1 kit

Product images

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Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol CYFIP1
Locus ID 23191
Kit Components

GA108110G1, CYFIP1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA108110G2, CYFIP1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA108110G3, CYFIP1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Reference Data
RefSeq NM_001033028, NM_001287810, NM_014608, NM_001324119, NM_001324120, NM_001324122, NM_001324123, NM_001324124, NM_001324125, NM_001324126
Synonyms P140SRA-1; SHYC; SRA-1; SRA1
Summary This gene encodes a protein that regulates cytoskeletal dynamics and protein translation. The encoded protein is a component of the WAVE regulatory complex (WRC), which promotes actin polymerization.This protein also interacts with the Fragile X mental retardation protein (FMRP) and translation initiation factor 4E to inhibit protein translation. A large chromosomal deletion including this gene is associated with increased risk of schizophrenia and epilepsy in human patients. Reduced expression of this gene has been observed in various human cancers and the encoded protein may inhibit tumor invasion. [provided by RefSeq, May 2017]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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