Human EFR3A activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	EFR3A
Locus ID	23167
Kit Components	GA108089G1, EFR3A gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA108089G2, EFR3A gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA108089G3, EFR3A gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001323553, NM_001323554, NM_001323555, NM_001323556, NM_001323557, NM_001323558, NM_015137, NR_136615, NR_136616
Summary	The protein encoded by this gene is part of a complex that plays a role in maintaining an active pool of phosphatidylinositol 4-kinase (PI4K) at the plasma membrane. This protein is thought to be a peripheral membrane protein that associates with the plasma membrane through palmitoylation. Studies indicate that this gene product plays a role in controlling G protein-coupled receptor (GPCR) activity by affecting receptor phosphorylation. Whole exome sequencing studies have implicated mutations in this gene with autism spectrum disorders. [provided by RefSeq, Apr 2016]

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